InFine Chemical Intermediate Synthesis, temperature control is directly linked to reaction selectivity, impurity control, solvent exchange efficiency, crystallization behavior, and batch reproducibility. Chemie’s heat transfer fluid portfolio helps plants manage these demands across jacketed reactors, heat exchangers, evaporators, reboilers, and purification systems.E200, operating from-85 to 230°Cwith1.20 mm²/s at 40°Cand apour point below -85°C, supports ultra-low-temperature synthesis and rapid thermal cycling.E230andE250, with ranges of-60 to 230°Cand-40 to 250°C, combine low-temperature fluidity, strong thermal stability, and long service life for flexible reactor heating and cooling. For broader process windows,E330delivers-49 to 315°C,4.04 mm²/s at 40°C, and a-68°C pour point, enabling reliable circulation during cold starts and stable control through demanding reaction stages.E350extends thermal capability to350°Cwhile offering low kinematic viscosity, low system pressure, and exceptional thermal stability for higher-temperature synthesis and rectification duties. Meanwhile,XT-1 / XT-2 / XT-3 / XT-4broaden system-matching flexibility for customized low-temperature integration, helping producers optimize transition control, reduce thermal stress, and sustain safe, efficient, continuous operation across the full intermediate synthesis workflow